Arterial wall stiffness and reduced arterial dilation are the first signs of cardiovascular diseases that can be measured. The Physical Activity and Nutrition in Children Study (PANIC) carried out in the Institute of Biomedicine at the University of Eastern Finland shows that low levels of physical activity, weaker physical fitness and higher body fat content are linked to arterial stiffness already in 6-8 year-old children. The study sample included 160 children, and the findings were published in Scandinavian Journal of Medicine and Science in Sports.
Physically active and fit persons have more flexible arterial walls already in childhood
The study showed that better physical fitness, plenty of leisure time physical activity and a low body fat percentage were associated with more flexible arterial walls already in primary school children. An analysis of the joint effects of these factors shows that only physical fitness was independently linked to arterial stiffness. Children whose physical fitness was better than that of their peers also had a better arterial dilation capacity during physical exercise.
Furthermore, the study showed that children with weak physical fitness combined with a high body fat percentage or low levels of physical activity also had the stiffest arteries. Moreover, higher arterial stiffness was also found in children with low levels of physical activity combined with a high body fat percentage. Children with the most physical activity or with the best physical fitness had the most flexible arteries and the best arterial dilation capacity.
Prevention of cardiovascular diseases best begun in childhood
The PANIC Study has earlier shown that the cumulation of risk factors for type 2 diabetes and vascular diseases in people who are overweight and physically passive begins already in childhood. This is a major concern because the cumulation of risk factors in childhood significantly increases the risk of type 2 diabetes, vascular diseases and premature death in adulthood. The study published now shows measurable adverse changes in the arteries of children with less physical activity, weaker physical fitness and higher body fat content.
The findings suggest that a lifestyle intervention in childhood can reduce the risk of cardiovascular diseases later in life. Another finding of the study deserving special attention is the association of better physical fitness with better arterial health, suggesting that especially regular, high-intensity physical exercise can be beneficial for arterial health.
PANIC Study – a source of scientifically valuable data on children’s health
The Physical Activity and Nutrition in Children Study, PANIC, is an on-going lifestyle intervention study. A total of 512 children aged 6 to 8 years participated in the onset measurements in 2007–2009. The study applies scientifically sound methods to extensively study the lifestyles, health and well-being of children. The study provides novel information on children’s physical activity and passivity, nutrition, physical condition, body composition, metabolism, vascular system, brain function, oral health, life quality, effects of exercise and nutrition on children’s health and well-being, and their effects on health care costs.
For further information, please contact:
Aapo Veijalainen, Lic.Med., Institute of Biomedicine, tel. +358409373828
Timo A. Lakka, Professor of Medical Physiology, Internal Medicine Specialist, Institute of Biomedicine, tel. +358407707329
Website of the Physical Activity and Nutrition in Children (PANIC) Study: www.